By Peter N. Robinson,Sebastian Bauer
Introduction to Bio-Ontologies explores the computational history of ontologies. Emphasizing computational and algorithmic matters surrounding bio-ontologies, this self-contained textual content is helping readers comprehend ontological algorithms and their applications.
The first a part of the ebook defines ontology and bio-ontologies. It additionally explains the significance of mathematical good judgment for realizing thoughts of inference in bio-ontologies, discusses the likelihood and records themes valuable for knowing ontology algorithms, and describes ontology languages, together with OBO (the preeminent language for bio-ontologies), RDF, RDFS, and OWL.
The moment half covers major bio-ontologies and their purposes. The booklet provides the Gene Ontology; upper-level ontologies, akin to the elemental Formal Ontology and the Relation Ontology; and present bio-ontologies, together with numerous anatomy ontologies, Chemical Entities of organic curiosity, series Ontology, Mammalian Phenotype Ontology, and Human Phenotype Ontology.
The 3rd a part of the textual content introduces the main graph-based algorithms for bio-ontologies. The authors speak about how those algorithms are utilized in overrepresentation research, model-based tactics, semantic similarity research, and Bayesian networks for molecular biology and biomedical applications.
With a spotlight on computational reasoning themes, the ultimate half describes the ontology languages of the Semantic net and their purposes for inference. It covers the formal semantics of RDF and RDFS, OWL inference principles, a key inference set of rules, the SPARQL question language, and the cutting-edge for querying OWL ontologies.
Software and knowledge designed to counterpoint fabric within the textual content can be found at the book’s site: http://bio-ontologies-book.org the location presents the R Robo package deal constructed for the e-book, besides a compressed archive of knowledge and ontology documents utilized in many of the workouts. It additionally deals teaching/presentation slides and hyperlinks to different proper websites.
This e-book offers readers with the root to exploit ontologies as a place to begin for brand spanking new bioinformatics examine initiatives or to help present molecular genetics study tasks. through providing a self-contained advent to OBO ontologies and the Semantic internet, it bridges the space among either fields and is helping readers see what each one can give a contribution to the research and knowing of biomedical data.
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